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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
pdgf-pdgfr
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "pdgf-pdgfr" in MCE Product Catalog:
Cat. No.: HY-42933
CAS No.: 190728-25-7
Target:
Research Areas:
PDGFR-IN-2 (Compound 16C) is a 4-phenoxyquinoline derivative. PDGFR-IN-2 is a platelet-derived growth factor receptor (PDGFr) inhibitor (IC50: 0.20 μM). PDGFR-IN-2 inhibits the activity of PDGFr tyrosine kinase .
Cat. No.: HY-175212
PDGFRA-IN-1 (Compound 4p) is a Platelet-derived growth factor receptor A (PDGFRA) inhibitor with an IC50 of 1.25 μM. PDGFRA-IN-1 has a significant anticancer activity and potently kills cancer cells including primary patient-derived glioma cells .
PDGFR-IN-1 (compound 7m) is a potent and orally active PDGFR (platelet-derived growth factor receptor) inhibitor, with IC50 values of 2.4 and 0.9 nM for PDGFRα and PDGFRβ, respectively. PDGFR-IN-1 displays robust antitumor effects and low toxicity, and can be used to study osteosarcoma .
Cat. No.: HY-187366
PDGFRβ-IN-1 is an orally active PDGFRβ inhibitor with an IC50 of 3.9 nM against human PDGFRβ. PDGFRβ-IN-1 selectively inhibits PDGFRβ, blocks its downstream signaling pathways, and promotes its degradation via a non-classical pathway. PDGFRβ-IN-1 inhibits cancer cell proliferation, migration and colony formation, and induces cancer cell apoptosis. PDGFRβ-IN-1 suppresses tumor growth in xenograft models. PDGFRβ-IN-1 can be used for the research of hepatocellular carcinoma .
Cat. No.: HY-P82180
Synonyms: pdgfRB; pdgfR; pdgfR1; pdgfRβ; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P83737
Synonyms: pdgfRB; pdgfR; pdgfR1; pdgfRβ; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P82180A
Synonyms: pdgfRB; pdgfR; pdgfR1; pdgfRβ; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P810636
Synonyms: pdgfRB; pdgfR; pdgfR1; pdgfRβ; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P810635
Synonyms: pdgfRB; pdgfR; pdgfR1; pdgfRβ; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P86661
Synonyms: pdgf Receptor alpha; Platelet–dirived growth factor receptor-alpha; alpha platelet derived growth factor receptor; CD 140a; CD140a; CD140a antigen; MGC74795; pdgf alpha chain; pdgf R alpha; pdgfR 2; pdgfR A; pdgfR alpha; pdgfR2; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; PGFRA_HUMAN.
Cat. No.: HY-P80510
Synonyms: CD140a, pdgfR2, RHEpdgfRA, pdgfRA, Platelet-derived growth factor receptor alpha, pdgf-R-alpha, pdgfR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, pdgfR-2
Cat. No.: HY-P85320
Synonyms: pdgfRB; pdgfR; pdgfR1; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P86327
Synonyms: pdgfRB; pdgfR; pdgfR1; Platelet-derived growth factor receptor beta; pdgf-R-beta; pdgfR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
Cat. No.: HY-P72495
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: pdgfRA; CD140a Antigen; Platelet Derived Growth Factor Receptor Alpha; pdgf-R-Alpha; pdgfR2; pdgfR-2; Platelet-Derived Growth Factor Receptor Alpha; GAS9; CD140a; Platelet-Derived Growth Factor Receptor-Like Protein; Platelet-Derived Growth Factor Recepto
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
