1 Result for "

phosphorylated PDID

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "phosphorylated PDID" in MCE Product Catalog:

Cat. No.: HY-P11661
CAS No.: 1334159-03-3
Research Areas:  

Inflammation/Immunology

DC-peptoid-1 is a specific binder and crosslinker targeting the phosphorylated Brd4 PDID domain, with a dissociation constant (Kd) of approximately 50-100 μM for human-derived targets. DC-peptoid-1 only binds to phosphorylated PDID and fails to recognize the non-phosphorylated form or other domains (such as Brd4 598-785). DC-peptoid-1 effectively crosslinks with the target protein both in solution and cell lysates. It can successfully capture phosphorylated PDID from complex systems via immobilization, without binding to bacterial-derived non-phosphorylated proteins or other non-specific phosphoproteins. DC-peptoid-1 has the potential to serve as a phosphoprotein-specific antibody substitute for applications such as immunoaffinity purification .
loading...
    loading...