4 Results for "

podofilox

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "podofilox" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-15552
CAS No.: 518-28-5
Purity:  99.92%
Synonyms: Podophyllotoxin
Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
Cat. No.: HY-15552S
Podofilox-d6 is the deuterium labeled Podofilox. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II .
Cat. No.: HY-15552R
CAS No.: 518-28-5
Synonyms: Podophyllotoxin (Standard)
Podofilox (Standard) is the analytical standard of Podofilox. This product is intended for research and analytical applications. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
Cat. No.: HY-106122
CAS No.: 105655-99-0
Synonyms: VP 19
Research Areas:  

Cancer

NK-611 (VP 19) is an epipodophyllotoxin derivative. NK-611 induces DNA double-strand breaks by inhibiting topoisomerase II (IC50 = 56 μM). NK-611 does not inhibit microtubule polymerization, thus avoiding the side effects of the parent compound, Podofilox (HY-15552). NK-611 exhibits broad-spectrum antitumor activity and demonstrates potent efficacy in in vivo models of leukemia. NK-611 can be used in cancer research .