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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
primary mouse embryonic fibroblasts
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "primary mouse embryonic fibroblasts" in MCE Product Catalog:
Cat. No.: HY-184507
CAS No.: 2975257-92-0
Target:
Research Areas:
(R,R,R)-AHPC is an E3 ubiquitin ligase ligand and serves as one of the E3 ligands for R4VPL3-1 (HY-184506). R4VPL3-1 is a molecular glue targeting RNF4 and VHL, which binds to and modifies GPX4 to inhibit its anti-ferroptosis function. R4VPL3-1 induces iron-dependent lipid peroxidation and ferroptosis-mediated rapid cell death in cancer cells. R4VPL3-1 can be used for cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
