1 Result for "

proteosome

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "proteosome" in MCE Product Catalog:

Cat. No.: HY-158239
CAS No.: 3037165-65-1
Purity:  98.36%
Research Areas:  

Cancer

MS181 is a BMI1 and RING1B degrader with antiproliferative activity. MS181 induces degradation via an EED-, CRBN-, and ubiquitin-proteosome system-dependent pathway, with preferential targeting over PRC2 components. MS181 acts in VHL-defective cancer cells. MS181 serves as a chemical biology tool to study PRC1 roles in cancer. MS181 can be used for the research of myelogenous leukemia, renal cell carcinoma, metastatic prostate cancer, triple negative breast cancer .
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