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purine modification

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Drug Metabolite (1) Nucleoside Antimetabolite/Analog (1)
By Research Areas:	Metabolic Disease (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

1,7-Dimethyluric acid	Biochemical Assay Reagents Drug Metabolite	Others
1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H₂O₂, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions .

6-Thio-cGMP	Nucleoside Antimetabolite/Analog	Others
6-Thio-cGMP is an analog of cyclic guanosine monophosphate (cGMP) .

Xanthine dehydrogenase, Microorganism	Biochemical Assay Reagents	Metabolic Disease
Xanthine dehydrogenase, Microorganism (EC 1.17.1.4) belongs to the molybdenum-containing hydroxylase family and participates in the oxidative metabolism of purines. Xanthine dehydrogenase, Microorganism (EC 1.17.1.4) is a homodimer and can be converted into xanthine oxidase through reversible thiol oxidation or irreversible proteolytic modification.

1,7-Dimethyluric acid	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Neurological Disease Classification of Application Fields Disease markers Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents Drug Metabolite
1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H₂O₂, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions .

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