2 Results for "

radioprotection

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "radioprotection" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-137864
CAS No.: 31098-42-7
Purity:  ≥95.0%
Synonyms: WR-1065
Target:  

MDM-2/p53

Research Areas:  

Cancer

Amifostine thiol (WR-1065) is an active metabolite of the cytoprotector Amifostine (HY-B0639). Amifostine thiol is a cytoprotective agent with radioprotective abilities. Amifostine thiol activates p53 through a JNK-dependent signaling pathway .
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Cat. No.: HY-112477
CAS No.: 724708-21-8
Synonyms: Hymenialdisine analogue-1
Research Areas:  

Cancer

Chk2-IN-1 (compound 1) is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), with IC50s of 13.5 nM and 220.4 nM for Chk2 and Chk1, respectively. Chk2-IN-1 can elicit a strong ataxia telangiectasia mutated (ATM)-dependent Chk2-mediated radioprotection effect .
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