3 Results for "

secukinumab

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "secukinumab" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-P9927
CAS No.: 1229022-83-6
Synonyms: AIN457

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-P9927A
CAS No.: 1229022-83-6

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .
loading...
    loading...
Cat. No.: HY-P991261

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CJM112 is a fully human IgG1/κ monoclonal antibody inhibitor targeting IL-17A, which binds to IL-17A and the IL-17AF heterodimer with high affinity, with KD values of 5.7 pM and <11 pM, respectively. CJM-112 exerts anti-inflammatory effects by neutralizing IL-17A, and reduces the Psoriasis Area and Severity Index in a time- and dose-dependent manner. CJM-112 also exhibits anti-inflammatory activity and improves disease severity in studies of hidradenitis suppurativa. CJM-112 shows favorable biosafety and tolerability. CJM-112 can be used in studies related to psoriasis and hidradenitis suppurativa .
loading...
    loading...