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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
thyrotoxicosis
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "thyrotoxicosis" in MCE Product Catalog:
Cat. No.: HY-127024A
CAS No.: 1073179-55-1
Target:
Research Areas:
TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRα/β) antagonist (IC50=47 nM). TR antagonist 2 competes with triiodothyronine (T3) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves' disease) and thyrotoxicosis .
Cat. No.: HY-186138
CAS No.: 1073180-47-8
Target:
Research Areas:
TR modulator-1 (compound 10c) is a selective thyroid hormone receptor (TR) modulator. TR modulator-1 can be used in the research of hyperthyroidism and thyrotoxicosis .
Cat. No.: HY-186138A
Target:
Research Areas:
TR modulator-1 (compound 10c) bromide is a selective thyroid hormone receptor (TR) modulator. TR modulator-1 bromide can be used in the research of hyperthyroidism and thyrotoxicosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
