1 Result for "

urea efflux

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "urea efflux" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-128129
CAS No.: 892742-76-6
Purity:  99.68%
Target:  

Urea Transporter

Research Areas:  

Metabolic Disease

UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
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