Azapetine
Azapetine is an α-adrenergic receptor antagonist, with a IC50 of 0.205 μM against rat α1-adrenergic receptors and a IC50 of 1.3 μM against rat α2-adrenergic receptors. Azapetine blocks α1/α2-adrenergic receptor-mediated contraction of blood vessels and vascular smooth muscles. Azapetine can be used for the research of peripheral vascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 146-36-1
- Formula: C17H17N
- Molecular Weight:235.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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All Adrenergic Receptor Isoforms
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Biological Activity
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rat α1-adrenergic receptor 0.205 μM (IC50) |
rat α2-adrenergic receptor 1.3 μM (IC50) |
Azapetine (45-60 min) exhibits higher binding affinity for α1-adrenergic receptors than for α2-adrenergic receptors in isolated rat brain cell membranes, with an IC50 of 0.205 μM for α1-adrenergic receptors and 1.3 μM for α2-adrenergic receptors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 146-36-1
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Molecular Weight 235.32
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Formula C17H17N
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SMILES
C=CCN1CC2=C(C3=C(C1)C=CC=C3)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Azapetine Related Classifications
HY-181635 Related Classifications
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