Lama3 - laminin subunit alpha 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 307582

Summary

Predicted to enable signaling receptor binding activity. Involved in cell-cell adhesion and hemidesmosome assembly. Located in adherens junction and hemidesmosome. Part of laminin-3 complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Lama3 Products (2)

mRNA Protein Name
NM_001393748.1 NP_001380677.1 laminin subunit alpha-3 isoform B precursor
NM_173306.2 NP_775428.2 laminin subunit alpha-3 isoform A precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16608848 RGD
Biological Process GO Annotation Evidence References Source
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
16608848 RGD
involved in hemidesmosome assembly IMP
IMP: Inferred from mutant phenotype
8923212 RGD
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
16608848 RGD
located in hemidesmosome IDA
IDA: Inferred from direct assay
8923212 RGD
part of laminin-3 complex IDA
IDA: Inferred from direct assay
8923212 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit alpha-3

  • laminin 5 alpha 3

  • laminin, alpha 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07499 LAMA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07500 LAMA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20050 Lama3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26554 Lama3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lama3 NCBI NCBI:3909