FUT10 - fucosyltransferase 10 Gene

Also Known as FUCTX

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84750

About FUT10

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:33,308,061-33,473,146 (from NCBI)

This gene has 11 transcripts (splice variants), 249 orthologues and 7 paralogues. Ubiquitous expression in ovary (RPKM 2.0), placenta (RPKM 1.5) and 25 other tissues.

Summary

Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to act upstream of or within cerebral cortex radially oriented cell migration and neuronal stem cell population maintenance. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FUT10 Products (1)

mRNA Protein Name
NM_032664.3 NP_116053.3 alpha-(1,3)-fucosyltransferase 10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fucosyltransferase activity IDA
IDA: Inferred from direct assay
19088067 GOA
Biological Process GO Annotation Evidence References Source
involved in N-glycan fucosylation IDA
IDA: Inferred from direct assay
19088067 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FUT10 Protein Structure

Glyco_transf_10

Glyco_transf_10: Glycosyltransferase family 10 (fucosyltransferase) C-term (13 - 398)

  • 0
  • 100
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  • 400
  • 479 a.a.
Protein Preferred Names Protein Names

alpha-(1,3)-fucosyltransferase 10

  • alpha (1,3) fucosyltransferase

Recombinant FUT10 Proteins

Cat. No. Product Name Accession Purity
HY-P76941 FUT10 Protein, Human (HEK293, His) Q6P4F1-1 (L32-D479) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Dowling-Degos Disease

  • Reticular Pigment Anomaly Of Flexures

  • Dark Dot Disease

  • Reticulate Acropigmentation Of Kitamura

  • Dowling-Degos Kitamura Disease

  • Kitamura Reticulate Acropigmentation

  • Ddd

  • Dowling-Degos-Kitamura Disease

  • Reticular Pigmented Anomaly Of Flexures
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05151 FUT10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21578 Fut10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28096 Fut10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FUT10 VGNC VGNC:41012
Macaca mulatta FUT10 VGNC VGNC:72745
Bos taurus FUT10 VGNC VGNC:29148
Felis catus FUT10 VGNC VGNC:62392
Rattus norvegicus FUT10 RGD RGD:1359164
Mus musculus FUT10 MGD MGI:2384748
Others FUT10 NCBI