L-689502
L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.
For research use only. We do not sell to patients.
- CAS No.: 138483-63-3
- Formula: C39H51N3O7
- Molecular Weight:673.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 1 nM (HIV-l protease)[1]
In Vitro
Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 138483-63-3
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Molecular Weight 673.84
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Formula C39H51N3O7
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SMILES
O=C(OC(C)(C)C)N[C@@H](CC1=CC=CC=C1)[C@@H](O)C[C@@H](CC2=CC=C(OCCN3CCOCC3)C=C2)C(N[C@@H]4[C@H](O)CC5=C4C=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-689502 Related Classifications
HY-U00261 Related Classifications
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