PK14105
Based on 1 Customer Validation
PK14105 is identified as a potential PBBS receptor in PET research biological evaluation.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.59%
- CAS No.: 107257-28-3
- 화학식: C21H20FN3O3
- 분자량:381.40
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Chemical Information
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CAS No. 107257-28-3
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Appearance Solid
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분자량 381.40
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화학식 C21H20FN3O3
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Color White to off-white
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SMILES
O=C(C1=CC2=C(C(C3=CC([N+]([O-])=O)=CC=C3F)=N1)C=CC=C2)N(C)C(C)CC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
용액&용해도
DMSO : ≥ 30 mg/mL (78.66 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Pascali C et al. The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites. Int J Rad Appl Instrum A. 1990;41(5):477-82. [Content Brief]
[2]. Franklin C. Wong et al. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations. Biomed Res Int. 2013, 503095. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6219 mL | 13.1096 mL | 26.2192 mL | 65.5480 mL |
| 5 mM | 0.5244 mL | 2.6219 mL | 5.2438 mL | 13.1096 mL | |
| 10 mM | 0.2622 mL | 1.3110 mL | 2.6219 mL | 6.5548 mL | |
| 15 mM | 0.1748 mL | 0.8740 mL | 1.7479 mL | 4.3699 mL | |
| 20 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2774 mL | |
| 25 mM | 0.1049 mL | 0.5244 mL | 1.0488 mL | 2.6219 mL | |
| 30 mM | 0.0874 mL | 0.4370 mL | 0.8740 mL | 2.1849 mL | |
| 40 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6387 mL | |
| 50 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3110 mL | |
| 60 mM | 0.0437 mL | 0.2185 mL | 0.4370 mL | 1.0925 mL |