2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. 3α-HSD

3α-HSD

3α-Hydroxysteroid dehydrogenase

3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds. 3α-HSD catalyzes the chemical reaction of conversion of 3-ketosteroids into 3α-hydroxysteroids. 3α-HSD has various protein isoforms (isozymes). The most studied isoforms are type 1 (AKR1C4), type 2 (AKR1C3) and type 3 (AKR1C2).

3α-HSD Related Products (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118819
    5-Bromo-3-phenyl salicylic acid
    		Inhibitor 98.00%
    5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM.
    5-Bromo-3-phenyl salicylic acid