3α-HSD
3α-Hydroxysteroid dehydrogenase
3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds. 3α-HSD catalyzes the chemical reaction of conversion of 3-ketosteroids into 3α-hydroxysteroids. 3α-HSD has various protein isoforms (isozymes). The most studied isoforms are type 1 (AKR1C4), type 2 (AKR1C3) and type 3 (AKR1C2).
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3α-HSD Related Products (3)
Related Products (3)
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3α-Hydroxysteroid Dehydrogenase, Microorganism
0 Images3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism.
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5-Bromo-3-phenyl salicylic acid
0 Images5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM.
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3α-Hydroxysteroid Dehydrogenase, Pseudomonas testosteroni
0 ImagesCat. No.: HY-P2901A3α-Hydroxysteroid Dehydrogenase, Pseudomonas testosteroni (EC 1.1.1.50) belongs to the oxidoreductase family. Its three substrates are androstenedione, NAD+, and NADP+, while its four products are 5α-androstane-3,17-dione, NADH, NADPH, and H+. 3α-Hydroxysteroid Dehydrogenase, Pseudomonas testosteroni, acts on the CH-OH group of the donor molecule, with NAD+ or NADP+ as the acceptor.
