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Cat. No.: HY-118819

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5-Bromo-3-phenyl salicylic acid

Name: 5-Bromo-3-phenyl salicylic acid
Brand: MedChemExpress
SKU: HY-118819
Price: 160.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with K_i of 140 nM.

For research use only. We do not sell to patients.

Purity: 98.00%
CAS No.: 99514-99-5
Formula: C₁₃H₉BrO₃
Molecular Weight:293.11

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

5-Bromo-3-phenyl salicylic acid Chemical Structure

CAS No.: 99514-99-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with K_i of 140 nM^[1].

IC₅₀ & Target

AKR1C1

140 nM (Ki)

In Vitro

5-Bromo-3-phenyl salicylic acid (10 μM) inhibits metabolism of progesterone in cell BAECs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 99514-99-5
Appearance Solid
Molecular Weight 293.11
Formula C₁₃H₉BrO₃
Color Off-white to light yellow
SMILES

O=C(C1=CC(Br)=CC(C2=CC=CC=C2)=C1O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1). J Med Chem. 2009 May 28;52(10):3259-64. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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5-Bromo-3-phenyl salicylic acid

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Auranofin (Standard)

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Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

5-Bromo-3-phenyl salicylic acid

AKR1C1-IN-1

ES 936

Auranofin

Trimidox hydrochloride

PMX464

Quercetin 3-gentiobioside

Exisulind

Soyasaponin Ba

Ganoderic acid C6

4′-Hydroxyflavone

Auranofin (Standard)

Soyasaponin Ba (Standard)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

5-Bromo-3-phenyl salicylic acid Related Classifications

HY-118819 Related Classifications

Bioz