3α-Hydroxysteroid Dehydrogenase, Microorganism
Based on 1 Customer Validation
3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism.
For research use only. We do not sell to patients.
- CAS No.: 9028-56-2
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Product Information
This product is a genetically recombinant product and has no animal origin. 3α-Hydroxysteroid dehydrogenase is used clinically to catalyze the dehydrogenation reaction of hydroxysteroids and is used for the clinical detection of total bile acid.
Molecular weight: about 28 kDa (SDS-PAGE detection)
Isoelectric point: 4.8
Optimum pH: 7.0-9.0
Inhibitors: Hg2+, Ag+, etc.
Instructions
Dissolved in ddH2O at concentrations below 50 mg/mL to avoid repeated freezing and thawing. Or dissolve in buffer according to specific experimental references.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1.1.1.50
≥50 U/mg protein
One unit is defined as the amount of enzyme required to oxidize 1 μmol androsterone per min at pH 8.9 at 25°C
Chemical Information
-
CAS No. 9028-56-2
-
Appearance Solid
-
Color White to off-white
-
SMILES
[3a-Hydroxysteroid Dehydrogenase, Microorganism]
-
Synonyms
3α-HSD
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : 50 mg/mL (Need ultrasonic)
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3α-Hydroxysteroid Dehydrogenase, Microorganism Related Classifications
HY-P2901 Related Classifications
Powered by Bioz