2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. MAP3K
  5. MAP3K12/DLK/Pref-1 Isoform

MAP3K12/DLK/Pref-1

 

MAP3K12/DLK/Pref-1 Related Products (2):

Cat. No. Product Name Effect Purity
  • HY-111277
    CEP-14513
    		Inhibitor
    CEP-14513 is an ALK inhibitor with an IC50 of 4 nM. CEP-14513 also inhibits insulin receptor, VEGFR2, TIE2 and DLK kinases, but does not inhibit MET, IKKβ, or CDK1/2/5. CEP-14513 induces cancer cell apoptosis. CEP-14513 is applicable to research related to non-small cell lung cancer, anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, and diffuse large B-cell lymphoma.
  • HY-181662
    DLK-IN-2
    		Inhibitor
    DLK-IN-2 is a selective inhibitor of DLK and neuroprotective agent. DLK-IN-2 shows no significant inhibition against CYPs 3A4, 2D6 and 2C9. DLK-IN-2 inhibits acute axonal palmitoylation of DLK, blocks DLK-dependent pro-degenerative axon-to-soma retrograde signaling and suppresses c-Jun phosphorylation. DLK-IN-2 can be used for the mechanistic study of neurodegenerative diseases.