2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. MAP4K
  5. MAP4K Isoform
  6. MAP4K Degrader

MAP4K Degrader

MAP4K Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-163372
    PROTAC HPK1 Degrader-1
    		Degrader
    PROTAC HPK1 Degrader-1 (Compound B1) is a potent HPK1 degrader with DC50 value of 1.8 nM. PROTAC HPK1 Degrader-1 inhibits phosphorylation of the SLP76 protein with IC50 value of 496.1 nM. PROTAC HPK1 Degrader-1 is a bona fide HPK1-PROTAC degrader, which provided a potential tool for further HPK1 investigation in TCR signaling.