2893885-31-7
2893885-31-7
Chemical Structure
PROTAC HPK1 Degrader-2
- CAS No.: 2893885-31-7
- Formula:C43H47N9O4
- Molecular Weight:753.89
InChIKey: KIJGLIOLEIJTJM-UHFFFAOYSA-N
SMILES: CC1=C2C(CCN(CCC(N3CCN(C4=CC=C(N5C(NC(CC5)=O)=O)C=C4)CC3)=O)C2)=CC(C6=NC(C(C7=CC=C(C(N(C)C)=O)C(C)=C7)=CN8)=C8N=C6)=C1
Biological Activity: PROTAC HPK1 Degrader-2 (compound 3) is a PROTAC degrader targeting hematopoietic progenitor kinase MAP4K1/HPK1, with a DC50 of 23 nM in human PBMCs. PROTAC HPK1 Degrader-2 is applicable for cancer research[1].
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PROTAC HPK1 Degrader-2 | PROTAC HPK1 Degrader-2 (compound 3) is a PROTAC degrader targeting hematopoietic progenitor kinase MAP4K1/HPK1, with a DC50 of 23 nM in human PBMCs. PROTAC HPK1 Degrader-2 is applicable for cancer research. | |||||||||||||||||||||
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