2. Signaling Pathways
  3. Immunology/Inflammation
  4. Kallikrein
  5. KLK10 Isoform

KLK10

 

KLK10 Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-N16719
    Picrasidine J
    		Inhibitor
    Picrasidine J is a selective inhibitor targeting the KLK-10 protease and the ERK signaling pathway. Picrasidine J inhibits epithelial-mesenchymal transition (EMT) by upregulating E-Cadherin and ZO-1 and downregulating β-catenin and Snail, while simultaneously reducing KLK-10 expression and inhibiting ERK phosphorylation, thereby exhibiting significant anti-migratory and anti-invasive activity. Picrasidine J can inhibit the metastasis of head and neck squamous cell carcinoma (HNSCC) and is primarily used in anti-metastasis research for head and neck tumors.