2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Ketohexokinase
  5. KHK-A Isoform

KHK-A

 

KHK-A Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-180921
    GS-1291269
    		Inhibitor
    GS-1291269 is a potent and neutral ketohexokinase (KHK) inhibitor, with IC50s of 0.38 and 2.1 nM against KHK-C and KHK-A, respectively. GS-1291269 demonstrates liver and kidney fructose-1-phosphate (F1P) reduction in a fructose challenge model in rats. GS-1291269 can be used for kidney disease and metabolic-dysfunction-associated steatotic liver disease (MASLD) research.