2. Signaling Pathways
  3. Immunology/Inflammation
  4. Tim3

Tim3

T-Cell Immunoglobulin and Mucin Containing Protein-3; CD366

Tim3 is an immunoglobulin type protein expressed exclusively on the surface of differentiated Th1 cells. It is a co-inhibitory receptor immune checkpoint protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-171537
    TIM-3-ligand-1
    		Ligand
    TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a Ki value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy.
    TIM-3-ligand-1
  • HY-D2972
    Apotracker Red
    		Ligand
    Apotracker Red is a fluorogenic peptide (excitation/emission: 561/610 nm). Apotracker Red binds to PtdSer on the surface of cells. Apotracker Red rapidly and selectively stains Apoptotic cells but not viable cells. Apotracker Red can be used to detect cancer cell death in real time.
    Apotracker Red
  • HY-P991395
    TQB2618
    		Inhibitor
    TQB2618 is a human IgG4 monoclonal antibody (mAb) targeting TIM-3/HAVCR2/CD366. TQB2618 activates immune cell function and induces significant anti-tumor activity when used in combination with anti-PD-1 agents.
    TQB2618
Cat. No. Product Name / Synonyms Application Reactivity