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Cat. No.: HY-171537

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TIM-3-ligand-1

TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a K_i value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy.

For research use only. We do not sell to patients.

CAS No.: 2883237-01-0
Formula: C₁₈H₁₆ClN₅O₃S
Molecular Weight:417.87

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

TIM-3-ligand-1 Chemical Structure

CAS No.: 2883237-01-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a K_i value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy^[1].

Chemical Information

CAS No. 2883237-01-0
Molecular Weight 417.87
Formula C₁₈H₁₆ClN₅O₃S
SMILES

CS(=O)(NC1=CC=C(C2=CC3=C(NC(N4C3=NC(C)=N4)=O)C=C2Cl)C(C)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rietz TA, et al. Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3). J Med Chem. 2021 Oct 14;64(19):14757-14772. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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