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Art. -Nr.: HY-171537

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TIM-3-ligand-1

TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a K_i value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2883237-01-0
Formel: C₁₈H₁₆ClN₅O₃S
Molecular Weight:417.87

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

TIM-3-ligand-1 Chemical Structure

CAS. Nr.: 2883237-01-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a K_i value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy^[1].

Chemical Information

CAS. Nr. 2883237-01-0
Molecular Weight 417.87
Formel C₁₈H₁₆ClN₅O₃S
SMILES

CS(=O)(NC1=CC=C(C2=CC3=C(NC(N4C3=NC(C)=N4)=O)C=C2Cl)C(C)=C1)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Rietz TA, et al. Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3). J Med Chem. 2021 Oct 14;64(19):14757-14772. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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