CDCA8 Antibody (YA7970)
(Synonyms: BOR; BOREALIN; DasraB; MESRGP)CDCA8 Antibody (YA7970) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CDCA8.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
CDCA8 Antibody (YA7970) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CDCA8.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Full length human recombinant protein of human CDCA8 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDCA8 component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment
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Subcellular Localization
Nucleus, nucleolus,Cytoplasm,Cytoplasm, cytoskeleton, spindle,Chromosome, centromere
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Isoforms & Post-Translational Modification
Q53HL2: 280 amino acids, molecular weight 31323 Da.
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Subunit
May form homooligomers and homodimers
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SwissProt ID
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Synonyms
BOR; BOREALIN; DasraB; MESRGP
Documentation
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