DOCK2 Antibody (YA8613)

Cat. No.: HY-P88929: Data Sheet User Guide for Antibodies
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DOCK2 Antibody (YA8613) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DOCK2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

DOCK2 Antibody (YA8613) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DOCK2.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92608

Immunogen

Human recombinant protein fragment corresponding to amino acids 1544-1830 of human DOCK2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2

Subcellular Localization：Endomembrane system,Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon

Isoforms & Post-Translational Modification：Q92608 has two isomers: Q92608-1: 211948 Da (predicted); Q92608-2: 38461 Da (predicted).

Subunit：Homodimer (Probable)

Synonyms

FLJ46592; KIAA0209

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/baf3-cell.html [Content Brief]