PARVB Antibody (YA8599)
(Synonyms: CGI-56)PARVB Antibody (YA8599) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PARVB.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
PARVB Antibody (YA8599) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PARVB.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 41.5 kDa
Full length human recombinant protein of human PARVB produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PARVB is an Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration
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Subcellular Localization
Cell junction, focal adhesion,Cell membrane,Cytoplasm, cytoskeleton,Cell projection, lamellipodium,Cytoplasm, myofibril, sarcomere,Cytoplasm, myofibril, sarcomere, Z line
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Expression
Tissue_Specificity: Expressed predominantly in heart and skeletal muscle -
Isoforms & Post-Translational Modification
Q9HBI1 has three isomers: Q9HBI1-1: 41714 Da (predicted); Q9HBI1-2: 45183 Da (predicted); Q9HBI1-3: 37538 Da (predicted).
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Subunit
Interacts with DYSF
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SwissProt ID
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Synonyms
CGI-56
Documentation
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