PRMT2 Antibody (YA7866)
(Synonyms: HRMT1L1)PRMT2 Antibody (YA7866) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRMT2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
PRMT2 Antibody (YA7866) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRMT2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 48.9 kDa
Full length human recombinant protein of human PRMT2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PRMT2 is an Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation
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Subcellular Localization
Cytoplasm,Nucleus,Nucleus,Cytoplasm,Nucleus,Nucleus, nucleolus,Nucleus,Cytoplasm,Nucleus
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Expression
Tissue_Specificity: Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord -
Isoforms & Post-Translational Modification
P55345 has 7 isomers: P55345-1: 49042 Da (predicted); P55345-2: 31162 Da (predicted); P55345-3: 37167 Da (predicted); P55345-4: 32424 Da (predicted); P55345-5: 33543 Da (predicted); P55345-6: 25494 Da (predicted); P55345-7: 31193 Da (predicted).
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Subunit
Self-associates
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SwissProt ID
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Synonyms
HRMT1L1
Documentation
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