TLE2 Antibody (YA8149)
(Synonyms: ESG; ESG2; GRG2)TLE2 Antibody (YA8149) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TLE2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
TLE2 Antibody (YA8149) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TLE2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 79.7 kDa
Full length human recombinant protein of human TLE2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity)
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: In all tissues examined, mostly in heart, brain, and muscle -
Isoforms & Post-Translational Modification
Q04725 has three isomers: Q04725-1: 79841 Da (predicted); Q04725-2: 66678 Da (predicted); Q04725-3: 75364 Da (predicted).
Ubiquitinated by XIAP/BIRC4 -
Subunit
Homooligomer and heterooligomer with other family members
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SwissProt ID
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Synonyms
ESG; ESG2; GRG2
Documentation
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