3-Hydroxypyridine-d4
3-Hydroxypyridine-d4 is the deuterium labeled 3-Hydroxypyridine (HY-Y1129). 3-Hydroxypyridine is a compound that can be isolated from bamboo grass. As an endogenous photosensitizer present in human skin, 3-hydroxypyridine can mediate oxidative stress, proliferation inhibition and apoptosis of skin cells through UVA/UVB excitation.
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- CAS. Nr.: 2241864-90-2
- Formel: C5HD4NO
- Molecular Weight:99.12
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 2241864-90-2
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Unlabeled Cas 109-00-2
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Molecular Weight 99.12
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Formel C5HD4NO
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SMILES
[2H]C1=C([2H])C([2H])=C(O)C([2H])=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Atsushi Endo, et al. Bamboo grass extract and use of the same extract. JP2006298766A
[3]. L D Lukyanova, et al. Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. Bull Exp Biol Med. 2009 Oct148(4):587-91. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)