3-Mercaptopropionic acid NHS ester
Based on 1 publication(s) in Google Scholar
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 95.0%
- CAS. Nr.: 117235-10-6
- Formel: C7H9NO4S
- Molecular Weight:203.22
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Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 3-Mercaptopropionic acid NHS ester
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Biologische Aktivität
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 117235-10-6
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Appearance Liquid (Density: 1.40±0.1 g/cm3)
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Molecular Weight 203.22
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Formel C7H9NO4S
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Color Colorless to light yellow
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SMILES
O=C(ON1C(CCC1=O)=O)CCS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Spatiotemporal Dynamic Immunomodulation by Infection-Mimicking Gels Enhances Broad and Durable Protective Immunity Against Heterologous Viruses. [Abstract]2025 Jan 13:e2412116. PMID: 39804984
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (492.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (466 KB)
- English - EN (466 KB)
- Français - FR (466 KB)
- Deutsch - DE (466 KB)
- Norwegian - NO (466 KB)
- Español - ES (466 KB)
- Swedish - SV (466 KB)
- Italian - IT (466 KB)
- Korean - KR (466 KB)
- Portuguese - PT (466 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9208 mL | 24.6039 mL | 49.2078 mL | 123.0194 mL |
| 5 mM | 0.9842 mL | 4.9208 mL | 9.8416 mL | 24.6039 mL | |
| 10 mM | 0.4921 mL | 2.4604 mL | 4.9208 mL | 12.3019 mL | |
| 15 mM | 0.3281 mL | 1.6403 mL | 3.2805 mL | 8.2013 mL | |
| 20 mM | 0.2460 mL | 1.2302 mL | 2.4604 mL | 6.1510 mL | |
| 25 mM | 0.1968 mL | 0.9842 mL | 1.9683 mL | 4.9208 mL | |
| 30 mM | 0.1640 mL | 0.8201 mL | 1.6403 mL | 4.1006 mL | |
| 40 mM | 0.1230 mL | 0.6151 mL | 1.2302 mL | 3.0755 mL | |
| 50 mM | 0.0984 mL | 0.4921 mL | 0.9842 mL | 2.4604 mL | |
| 60 mM | 0.0820 mL | 0.4101 mL | 0.8201 mL | 2.0503 mL | |
| 80 mM | 0.0615 mL | 0.3075 mL | 0.6151 mL | 1.5377 mL | |
| 100 mM | 0.0492 mL | 0.2460 mL | 0.4921 mL | 1.2302 mL |
3-Mercaptopropionic acid NHS ester Related Classifications
HY-136159 Related Classifications
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