BN-50726
BN-50726 is a potent platelet-activating factor (PAF) receptor antagonist. BN-50726 inhibits PAF-induced effects (e.g., [3H]-serotonin release and hypotension) (IC50=5.40 nM). BN-50726 is promising for research of PAF-mediated pathological processes (e.g., inflammation, anaphylaxis, hypotension).
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- CAS. Nr.: 127279-06-5
- Formel: C34H48ClN5O2S2
- Molecular Weight:658.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 127279-06-5
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Molecular Weight 658.36
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Formel C34H48ClN5O2S2
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SMILES
CC1=NN=C2N1C3=C(C4=C(CN(S(=O)(CCCCCCCCCCCCCCCC)=O)CC4)S3)C(C5=CC=CC=C5Cl)=NC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Zarco P, et al. Involvement of platelet-activating factor and tumour necrosis factor in the pathogenesis of joint inflammation in rabbits. Clin Exp Immunol. 1992 May;88(2):318-23. [Content Brief]
[2]. Yue TL, et al. Pharmacologic profile of BN 50739, a new PAF antagonist in vitro and in vivo. Prostaglandins. 1990 May;39(5):469-80. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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