Boc-HyNic-PEG2-DBCO
Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Boc-HyNic-PEG2-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formel: C36H42N6O7
- Molecular Weight:670.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 670.75
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Formel C36H42N6O7
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SMILES
O=C(NCCOCCOCCC(NCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)=O)C4=CN=C(NNC(OC(C)(C)C)=O)C=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)