Calcrl - calcitonin receptor like receptor Gene
Also Known as CLR; Crlr; RNCLR; RATCRLR
Species: Rattus norvegicus
Summary
Predicted to enable Adrenomedullin binding activity; Adrenomedullin receptor activity; and Calcitonin gene-related peptide receptor activity. Involved in negative regulation of inflammatory response and negative regulation of smooth muscle contraction. Predicted to be located in endoplasmic reticulum; endosome; and lysosome. Predicted to be part of CGRP Receptor complex and Adrenomedullin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CALCRL (Calcitonin receptor like receptor). [provided by Alliance of Genome Resources, Apr 2022]
Calcrl Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_012717.3 | NP_036849.2 | calcitonin gene-related peptide type 1 receptor precursor |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in negative regulation of smooth muscle contraction |
IMP
IMP: Inferred from mutant phenotype
|
17363466 | RGD |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| is active in neuronal dense core vesicle |
IDA
IDA: Inferred from direct assay
|
17614212 | RGD |
| is active in synaptic vesicle |
IDA
IDA: Inferred from direct assay
|
17614212 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
calcitonin gene-related peptide type 1 receptor |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS01835 | CALCRL Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20140 | Calcrl Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26644 | Calcrl Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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