POU4F2 - POU class 4 homeobox 2 Gene

Also Known as BRN3B; BRN3.2; Brn-3b

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 5458

About POU4F2

Cytogenetic location: 4q31.22 Genomic coordinates (GRCh38): 4:146,638,893-146,642,474 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 17 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]

POU4F2 Products (1)

mRNA	Protein	Name
NM_004575.3	NP_004566.2	POU domain, class 4, transcription factor 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Verweise	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	17637757	GOA
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	23805044	GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17637757	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Verweise	Source
involved in MAPK cascade	IDA IDA: Inferred from direct assay	21241485	GOA
involved in estrogen receptor signaling pathway	IDA IDA: Inferred from direct assay	21241485	GOA
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	23805044	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17637757	GOA
involved in positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	23805044	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	19266028	GOA

Cellular Component GO Annotation	Evidence	Verweise	Source
located in nuclear speck	IDA IDA: Inferred from direct assay	19266028	GOA
located in nucleus	IDA IDA: Inferred from direct assay	7691107	GOA
part of transcription regulator complex	IGI IGI: Inferred from genetic interaction	17145718	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

POU4F2 Protein Structure

Pou

Homeobox

0
100
200
300
409 a.a.

Protein Preferred Names	Protein Names
POU domain, class 4, transcription factor 2	Brn3b POU domain transcription factor

POU4F2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	POU4F2	Q12837	KRTAP10-9	Homo sapiens	P60411	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP10-9	Homo sapiens	P60411	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP4-2	Homo sapiens	Q9BYR5	Validated Y2H	32296183
Intra	POU4F2	Q12837	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	32296183
Intra	POU4F2	Q12837	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP12-1	Homo sapiens	P59990	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP12-1	Homo sapiens	P59990	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP13-3	Homo sapiens	Q3SY46	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP19-7	Homo sapiens	Q3SYF9	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP5-6	Homo sapiens	Q6L8G9	Validated Y2H	32296183
Intra	POU4F2	Q12837	NFKBID	Homo sapiens	Q8NI38	Validated Y2H	32296183
Intra	POU4F2	Q12837	NFKBID	Homo sapiens	Q8NI38	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	NFKBID	Homo sapiens	Q8NI38	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP4-11	Homo sapiens	Q9BYQ6	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP9-3	Homo sapiens	Q9BYQ3	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP9-2	Homo sapiens	Q9BYQ4	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRT38	Homo sapiens	O76015	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRT38	Homo sapiens	O76015	Y2H Array	32296183
Intra	POU4F2	Q12837	KRT35	Homo sapiens	Q92764	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRT35	Homo sapiens	Q92764	Y2H Array	32296183
Intra	POU4F2	Q12837	KRT35	Homo sapiens	Q92764	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KPRP	Homo sapiens	Q5T749	Y2H Array	32296183
Intra	POU4F2	Q12837	KPRP	Homo sapiens	Q5T749	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KPRP	Homo sapiens	Q5T749	Validated Y2H	32296183
Intra	POU4F2	Q12837	MMADHC	Homo sapiens	Q9H3L0	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	MMADHC	Homo sapiens	Q9H3L0	Validated Y2H	32296183
Intra	POU4F2	Q12837	MMADHC	Homo sapiens	Q9H3L0	Y2H Array	32296183
Intra	POU4F2	Q12837	LCN2	Homo sapiens	P80188	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LCN2	Homo sapiens	P80188	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP12-3	Homo sapiens	P60328	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP12-3	Homo sapiens	P60328	Y2H Array	32296183
Intra	POU4F2	Q12837	LCE5A	Homo sapiens	Q5TCM9	Validated Y2H	32296183
Intra	POU4F2	Q12837	LCE5A	Homo sapiens	Q5TCM9	Y2H Array	32296183
Intra	POU4F2	Q12837	LCE5A	Homo sapiens	Q5TCM9	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	PCSK5	Homo sapiens	Q92824-2	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	PCSK5	Homo sapiens	Q92824-2	Validated Y2H	32296183
Intra	POU4F2	Q12837	PCSK5	Homo sapiens	Q92824-2	Y2H Array	32296183
Intra	POU4F2	Q12837	VWC2	Homo sapiens	Q2TAL6	Validated Y2H	32296183
Intra	POU4F2	Q12837	LCE1F	Homo sapiens	Q5T754	Validated Y2H	32296183
Intra	POU4F2	Q12837	LCE1F	Homo sapiens	Q5T754	Y2H Array	32296183
Intra	POU4F2	Q12837	LCE1F	Homo sapiens	Q5T754	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP4-4	Homo sapiens	Q9BYR3	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP9-8	Homo sapiens	Q9BYQ0	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP9-8	Homo sapiens	Q9BYQ0	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP9-8	Homo sapiens	Q9BYQ0	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP5-4	Homo sapiens	Q6L8H1	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP5-3	Homo sapiens	Q6L8H2	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP4-5	Homo sapiens	Q9BYR2	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP5-11	Homo sapiens	Q6L8G4	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP6-1	Homo sapiens	Q3LI64	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP6-1	Homo sapiens	Q3LI64	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP6-1	Homo sapiens	Q3LI64	Validated Y2H	32296183
Intra	POU4F2	Q12837	LHX2	Homo sapiens	P50458	Y2H Array	32296183
Intra	POU4F2	Q12837	LHX2	Homo sapiens	P50458	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP19-2	Homo sapiens	Q3LHN2	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP19-2	Homo sapiens	Q3LHN2	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP19-2	Homo sapiens	Q3LHN2	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LCE1C	Homo sapiens	Q5T751	Validated Y2H	32296183
Intra	POU4F2	Q12837	LCE1C	Homo sapiens	Q5T751	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LCE1C	Homo sapiens	Q5T751	Y2H Array	32296183
Intra	POU4F2	Q12837	CERCAM	Homo sapiens	Q5T4B2	Y2H Array	32296183
Intra	POU4F2	Q12837	CERCAM	Homo sapiens	Q5T4B2	Validated Y2H	32296183
Intra	POU4F2	Q12837	CERCAM	Homo sapiens	Q5T4B2	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	CHRDL2	Homo sapiens	Q6WN34-2	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	CHRDL2	Homo sapiens	Q6WN34-2	Validated Y2H	32296183
Intra	POU4F2	Q12837	CHRDL2	Homo sapiens	Q6WN34-2	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP19-6	Homo sapiens	Q3LI70	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP19-6	Homo sapiens	Q3LI70	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP19-6	Homo sapiens	Q3LI70	Validated Y2H	32296183
Intra	POU4F2	Q12837	RBP3	Homo sapiens	P10745	Y2H Array	32296183
Intra	POU4F2	Q12837	RBP3	Homo sapiens	P10745	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	FAM86C1P	Homo sapiens	Q9NVL1-2	Validated Y2H	32296183
Intra	POU4F2	Q12837	FAM86C1P	Homo sapiens	Q9NVL1-2	Y2H Array	32296183
Intra	POU4F2	Q12837	HIGD2B	Homo sapiens	Q4VC39	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	HIGD2B	Homo sapiens	Q4VC39	Validated Y2H	32296183
Intra	POU4F2	Q12837	HIGD2B	Homo sapiens	Q4VC39	Y2H Array	32296183
Intra	POU4F2	Q12837	CD46	Homo sapiens	P15529-3	Y2H Array	32296183
Intra	POU4F2	Q12837	CD46	Homo sapiens	P15529-3	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	NOTO	Homo sapiens	A8MTQ0	Y2H Array	32296183
Intra	POU4F2	Q12837	NOTO	Homo sapiens	A8MTQ0	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LYPD2	Homo sapiens	Q6UXB3	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LYPD2	Homo sapiens	Q6UXB3	Validated Y2H	32296183
Intra	POU4F2	Q12837	LYPD2	Homo sapiens	Q6UXB3	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP21-2	Homo sapiens	Q3LI59	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP21-2	Homo sapiens	Q3LI59	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP21-2	Homo sapiens	Q3LI59	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	POU4F2	Q12837	SPRY4	Homo sapiens	Q9C004	Y2H Array	32296183
Intra	POU4F2	Q12837	SPRY4	Homo sapiens	Q9C004	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	SPRY4	Homo sapiens	Q9C004	Validated Y2H	32296183
Intra	POU4F2	Q12837	IGFL1	Homo sapiens	Q6UW32	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	IGFL1	Homo sapiens	Q6UW32	Validated Y2H	32296183
Intra	POU4F2	Q12837	IGFL1	Homo sapiens	Q6UW32	Y2H Array	32296183
Intra	POU4F2	Q12837	CCN3	Homo sapiens	P48745	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	CCN3	Homo sapiens	P48745	Y2H Array	32296183
Intra	POU4F2	Q12837	DLX3	Homo sapiens	O60479	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	DLX3	Homo sapiens	O60479	Y2H Array	32296183
Intra	POU4F2	Q12837	PLSCR2	Homo sapiens	Q9NRY7	Y2H Array	32296183
Intra	POU4F2	Q12837	PLSCR2	Homo sapiens	Q9NRY7	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	PLSCR2	Homo sapiens	Q9NRY7	Validated Y2H	32296183
Intra	POU4F2	Q12837	LGALS13	Homo sapiens	Q9UHV8	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	LGALS13	Homo sapiens	Q9UHV8	Validated Y2H	32296183
Intra	POU4F2	Q12837	LGALS13	Homo sapiens	Q9UHV8	Y2H Array	32296183
Intra	POU4F2	Q12837	TRIM42	Homo sapiens	Q8IWZ5	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	TRIM42	Homo sapiens	Q8IWZ5	Validated Y2H	32296183
Intra	POU4F2	Q12837	TRIM42	Homo sapiens	Q8IWZ5	Y2H Array	32296183
Intra	POU4F2	Q12837	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP4-12	Homo sapiens	Q9BQ66	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP4-12	Homo sapiens	Q9BQ66	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRTAP4-12	Homo sapiens	Q9BQ66	Y2H Array	32296183
Intra	POU4F2	Q12837	RBPMS	Homo sapiens	Q93062-3	Y2H Array	32296183
Intra	POU4F2	Q12837	RBPMS	Homo sapiens	Q93062-3	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	RBPMS	Homo sapiens	Q93062-3	Validated Y2H	32296183
Intra	POU4F2	Q12837	CHIC2	Homo sapiens	Q9UKJ5	Validated Y2H	32296183
Intra	POU4F2	Q12837	CHIC2	Homo sapiens	Q9UKJ5	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	CHIC2	Homo sapiens	Q9UKJ5	Y2H Array	32296183
Intra	POU4F2	Q12837	HDHD3	Homo sapiens	Q9BSH5	Validated Y2H	32296183
Intra	POU4F2	Q12837	HDHD3	Homo sapiens	Q9BSH5	Y2H Array	32296183
Intra	POU4F2	Q12837	HDHD3	Homo sapiens	Q9BSH5	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	GRN	Homo sapiens	P28799	Y2H Array	32296183
Intra	POU4F2	Q12837	GRN	Homo sapiens	P28799	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP3-2	Homo sapiens	Q9BYR7	Y2H Array	32296183
Intra	POU4F2	Q12837	KRTAP3-2	Homo sapiens	Q9BYR7	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRTAP3-2	Homo sapiens	Q9BYR7	Validated Y2H	32296183
Intra	POU4F2	Q12837	RGS19	Homo sapiens	P49795	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	RGS19	Homo sapiens	P49795	Y2H Array	32296183
Intra	POU4F2	Q12837	IGFBP6	Homo sapiens	P24592	Y2H Array	32296183
Intra	POU4F2	Q12837	IGFBP6	Homo sapiens	P24592	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	CHRD	Homo sapiens	Q9H2X0	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	POU4F2	Q12837	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	POU4F2	Q12837	KRT31	Homo sapiens	Q15323	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Nonarteritic Anterior Ischemic Optic Neuropathy	Anterior Ischemic Optic Neuropathy Nonarteritic Anterior Ischemic Optic Neuropathy, Susceptibility To NAION Non-Arteritic Anterior Ischemic Optic Neuropathy Ischemic Optic Neuropathy Aion Optic Neuropathy, Ischemic Naion, Susceptibility To Optic Neuropathy, Anterior Ischemic Optic Neuropathy, Anterior Ischemic, Susceptibility To Non-Arteritic Anterior Ischaemic Optic Neuropathy Nonarteritic Anterior Ischaemic Optic Neuropathy Neuropathy, Optic, Ischemic, Nonarteritic Anterior, Susceptibility To Ion - [Ischemic Optic Neuropathy] Neuropathic Ischaemia Of N.Opticus Ischaemic Neuropathy Of Optic Nerve
Thrombophlebitis Migrans
Nutritional Optic Neuropathy
Optic Nerve Disease	Optic Neuropathy Disorder Of The Second Nerve Optic Nerve Disorder Optic Nerve Abnormality Of The Optic Nerve Optic Nerve Disorders Neuropathy, Optic Disorder Of The Optic Nerve
3-Methylglutaconic Aciduria, Type Iii	Optic Atrophy 3-Methylglutaconic Aciduria Type 3 Costeff Syndrome Mga3 Costeff Optic Atrophy Syndrome Optic Atrophy Plus Syndrome Infantile Optic Atrophy With Chorea And Spastic Paraplegia 3-Methylglutaconic Aciduria Type Iii Autosomal Recessive Optic Atrophy Plus Syndrome Autosomal Recessive Optic Atrophy Type 3 Opa3 Defect MGCA3 Mga, Type Iii Iraqi Jewish Optic Atrophy Plus Mga Type Iii Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia Iraqi-Jewish 'Optic Atrophy Plus' Optic Atrophy 3, Autosomal Recessive Opa3, Autosomal Recessive Opa3-Related 3-Methylglutaconic Aciduria Iraqi-Jewish Optic Atrophy Plus Atrophy Of Optic Disc 3-Alpha Methylglutaconic Aciduria Type Iii Optic Atrophy 3 Optic Atrophy Infantile With Chorea And Spastic Paraplegia Autosomal Recessive Opa3 Autosomal Recessive Optic Atrophy 3 3-Methylglutaconic Aciduria 3 3-Alpha-Methylglutaconic Aciduria Type 3 Optic Atrophy 3 Autosomal Recessive Atrophy, Optic Atrophy, Optic, Plus Syndrome Optic Nerve Atrophy Primary Optic Atrophy Oa - [Optic Atrophy] Second Cranial Nerve Atrophy Second Cranium Nerve Atrophy
Cone-Rod Dystrophy 2	Cone-Rod Dystrophy CORD2 Cone-Rod Retinal Dystrophy Rcrd2 Cone-Rod Retinal Dystrophy 2 Crd2 Cord Crd Retinal Cone-Rod Dystrophy Cone-Rod Retinal Dystrophy-2 Retinal Cone-Rod Dystrophy 2 Tapetoretinal Degeneration Cone-Rod Degeneration Cone Rod Dystrophy Dystrophy, Cone-Rod Dystrophy, Cone-Rod, Type 2 Retinitis Pigmentosa Retinitis Pigmentosa 2 Progressive Cone-Rod Dystrophy
Leber Plus Disease	Leber Congenital Amaurosis Lca Leber'S Amaurosis Leber'S Disease Amaurosis Congenita Of Leber Amaurosis Congenita Of Leber, Type 1 Lhon Plus Disease Congenital Absence Of The Rods And Cones Congenital Retinal Blindness Crb Congenital Amaurosis Of Retinal Origin Leber'S Congenital Amaurosis Leber Congenital Amaurosis 1 Leber'S Congenital Tapetoretinal Degeneration Leber'S Congenital Tapetoretinal Dysplasia Lca1 Leber Congenital Amaurosis Type 1 Retinal Blindness, Congenital Amaurosis, Leber Congenital Dysgenesis Neuroepithelialis Retinae Hereditary Epithelial Dysplasia Of Retina Hereditary Retinal Aplasia Heredoretinopathia Congenitalis Leber Abiotrophy Leber Congenital Tapetoretinal Degeneration Lebers Congenital Amaurosis Optic Atrophy, Hereditary, Leber
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Fundus Dystrophy	Retinal Dystrophy Retinal Dystrophies Dystrophy, Retinal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS10905	POU4F2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	POU4F2	VGNC	VGNC:33178
Macaca mulatta	POU4F2	VGNC	VGNC:76225
Mus musculus	POU4F2	MGD	MGI:102524
Canis familiaris	POU4F2	VGNC	VGNC:44831
Felis catus	POU4F2	VGNC	VGNC:68967
Rattus norvegicus	POU4F2	RGD	RGD:620075
Others	POU4F2	NCBI