PAO-Nap
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.
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- CAS. Nr.: 1613402-20-2
- Formel: C24H24AsN3O5
- Molecular Weight:509.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1613402-20-2
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Molecular Weight 509.39
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Formel C24H24AsN3O5
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SMILES
O[As](C1=CC=C(NC(CCCCCN(C(C2=CC=C(N)C3=CC=CC4=C23)=O)C4=O)=O)C=C1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PAO-Nap Related Classifications
HY-D1267 Related Classifications
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