3 Results for "

hypermodified

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "hypermodified" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-N10574
CAS. Nr.: 72496-59-4
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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1
1 Cited Publications
Art. -Nr.: HY-N10574A
CAS. Nr.: 86496-18-6
Target:  

Others

Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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Art. -Nr.: HY-W746941
CAS. Nr.: 52049-48-6
Synonyms: ms2io6A; cis-2-Methylthioribosylzeatin
Forschungsgebiete:  

Others

2-Methylthio-cis-zeatin riboside (ms2io6A) , a hypermodified adenosine derivative, is present in the transfer RNA of Salmonella ryphimurium.
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