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United States

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Cat. No.: HY-173452

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DT-23

DT-23 is a potent antifungal agent with an MIC₅₀ of 15 μg/mL. DT-23 inhibits recombinant Arg1 and Kcs1 with IC₅₀s of 0.6 and 0.68 μM, respectively.

For research use only. We do not sell to patients.

Formula: C₂₅H₂₆F₃N₇
Molecular Weight:481.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

DT-23 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DT-23 is a potent antifungal agent with an MIC₅₀ of 15 μg/mL. DT-23 inhibits recombinant Arg1 and Kcs1 with IC₅₀s of 0.6 and 0.68 μM, respectively^[1].

Chemical Information

Molecular Weight 481.52
Formula C₂₅H₂₆F₃N₇
SMILES

FC(F)(F)C1=CC=CC(CNC2=NC(NC(CC3)CCN3CC4=CC=CC=C4)=C5C(NC=N5)=N2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Desmarini D, et al. Synthesis of a New Purine Analogue Class with Antifungal Activity and Improved Potency against Fungal IP3-4K. ACS Infect Dis. 2025 Apr 11;11(4):940-953. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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