Morpholino A phosphoramidite
Morpholino A phosphoramidite is a specialized chemical building block used to synthesize Phosphorodiamidate Morpholino Oligomers (PMOs). Morpholino A phosphoramidite contains the adenine (A) nucleobase attached to a morpholine ring, fitted with a phosphoramidite group. PMOs are synthetic gene knockdown tools heavily used in developmental biology and targeted therapeutics to inhibit gene expression or alter RNA splicing.
For research use only. We do not sell to patients.
- CAS No.: 2243974-80-1
- Formula: C47H53N8O6P
- Molecular Weight:856.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
PMOs feature a neutral, uncharged backbone of methylenemorpholine rings linked by phosphorodiamidate groups unlike standard DNA/RNA that feature a negatively charged ribose-phosphate backbone[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2243974-80-1
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Molecular Weight 856.95
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Formula C47H53N8O6P
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SMILES
CC(C)N(C(C)C)P(OCCC#N)N(C1)C[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Morpholino A phosphoramidite Related Classifications
HY-17653 Related Classifications
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