Dnajb1 - DnaJ heat shock protein family (Hsp40) member B1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361384

About Dnajb1

Primary_assembly 19: 24,522,717-24,526,458 reverse strand.mRatBN7.2:CM026992.1

This gene has 1 transcript (splice variant), 432 orthologues and 15 paralogues. Biased expression in Testes (RPKM 393.), Adrenal (RPKM 23.5) and 9 other tissues.

Summary

Predicted to enable several functions, including ATPase binding activity; HSP70 protein binding activity; and chaperone binding activity. Involved in forebrain development. Located in several cellular components, including dendritic spine; postsynaptic cytosol; and sperm head. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DNAJB1 (DnaJ heat shock protein family (HSP40) member B1). [provided by Alliance of Genome Resources, Apr 2022]

Dnajb1 Products (1)

mRNA Protein Name
NM_001395149.1 NP_001382078.1 dnaJ homolog subfamily B member 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in forebrain development IEP
IEP: Inferred from expression pattern
9878698 RGD
Cellular Component GO Annotation Evidence References Source
located in dendritic spine IDA
IDA: Inferred from direct assay
9878698 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9878698 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
9878698 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
9878698 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
9878698 RGD
located in sperm head IDA
IDA: Inferred from direct assay
16955402 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Dnajb1 Protein Structure

DnaJ

DnaJ: COG0484 (0 - 339)

  • 0
  • 100
  • 200
  • 300
  • 340 a.a.
Protein Preferred Names Protein Names

dnaJ homolog subfamily B member 1

  • DnaJ (Hsp40) homolog, subfamily B, member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150072 DS89002333 Inhibitor 99.85% Unkown
HY-RS03861 DNAJB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-114461B (3S,17S)-FD-895 / Unkown
HY-RS03862 Dnajb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03863 Dnajb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnajb1 NCBI NCBI:3337