Afovirsen
Afovirsen is a 20-mer phosphorothioate oligonucleotide. It is complementary to the mRNA sequence for the translation initiation codon of the E2 protein vital to replication of HPV types 6 and 11.
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- CAS No.: 151356-08-0
- Formule: C192H269N57O107P19S19
- Masse moléculaire:6285.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 151356-08-0
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Masse moléculaire 6285.23
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Formule C192H269N57O107P19S19
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SMILES
[Afovirsen]
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Synonyms
ISIS 2105
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Crooke ST, Grillone LR, Tendolkar A, et al. A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts. Clin Pharmacol Ther. 1994;56(6 Pt 1):641-646. [Content Brief]
[2]. Crooke RM, Graham MJ, Cooke ME, Crooke ST. In vitro pharmacokinetics of phosphorothioate antisense oligonucleotides. J Pharmacol Exp Ther. 1995;275(1):462-473. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)