ALK5-IN-29
ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2785430-85-3
- Formule: C24H25FN8
- Masse moléculaire:444.51
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
IC50: ≤10 nM (ALK5/2); ≤100 nM (RD-SMAD receptor)[1]
ALK5-IN-29 (EX-06) has kinase inhibition of ALK5 with an IC50 value of ≤10 nM[1].
ALK5-IN-29 has kinase selectivity of ALK2/ALK5 with an IC50 value of ≤10 nM[1].
ALK5-IN-29 shows TGFB-RI inhibition (RD-SMAD receptor activity) with an IC50 value of ≤100 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2785430-85-3
-
Masse moléculaire 444.51
-
Formule C24H25FN8
-
SMILES
CC1=CC=CC2=C(NC3=NC(NC4=CC(CN5CCNCC5)=CC(F)=C4)=NC=C3)C=NN=C12
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALK5-IN-29 Related Classifications
HY-151277 Related Classifications
Powered by Bioz