2785430-85-3
2785430-85-3
Chemical Structure
ALK5-IN-29
- CAS No.: 2785430-85-3
- Formula:C24H25FN8
- Molecular Weight:444.51
IUPAC Name: N2-(3-fluoro-5-(piperazin-1-ylmethyl)phenyl)-N4-(8-methylcinnolin-4-yl)pyrimidine-2,4-diamine
InChIKey: DMKDGVBLGDMHMJ-UHFFFAOYSA-N
SMILES: CC1=CC=CC2=C(NC3=NC(NC4=CC(CN5CCNCC5)=CC(F)=C4)=NC=C3)C=NN=C12
Biological Activity: ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer[1].
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ALK5-IN-29 | ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer. | |||||||||||||||||||||
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References
Keywords
