ALKBH5-IN-3
Based on 1 Customer Validation
ALKBH5-IN-3 is a selective, cell active ALKBH5 inhibitor with an IC50 of 0.021 μM. ALKBH5-IN-3 stabilizes ALKBH5 in HepG2 cells, and increases m6A level in intact cells. ALKBH5-IN-3 can be used as a versatile chemical probe to explore the biological function of ALKBH5. ALKBH5-IN-3 can be used for the research of Cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.63%
- CAS No.: 1505579-77-0
- Formule: C11H7F3N2O3
- Masse moléculaire:272.18
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Membrane Protein-targeted Compound Library
HY-L149
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Highly Selective Inhibitors Library
HY-L158
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
Activité biologique
IC50: 21 nM (ALKBH5)[1]
Chemical Information
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CAS No. 1505579-77-0
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Appearance Solid
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Masse moléculaire 272.18
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Formule C11H7F3N2O3
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Color White to off-white
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SMILES
O=C(C1=NN(C2=CC=CC(C(F)(F)F)=C2)C(O)=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 31.25 mg/mL (114.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6740 mL | 18.3702 mL | 36.7404 mL | 91.8510 mL |
| 5 mM | 0.7348 mL | 3.6740 mL | 7.3481 mL | 18.3702 mL | |
| 10 mM | 0.3674 mL | 1.8370 mL | 3.6740 mL | 9.1851 mL | |
| 15 mM | 0.2449 mL | 1.2247 mL | 2.4494 mL | 6.1234 mL | |
| 20 mM | 0.1837 mL | 0.9185 mL | 1.8370 mL | 4.5925 mL | |
| 25 mM | 0.1470 mL | 0.7348 mL | 1.4696 mL | 3.6740 mL | |
| 30 mM | 0.1225 mL | 0.6123 mL | 1.2247 mL | 3.0617 mL | |
| 40 mM | 0.0919 mL | 0.4593 mL | 0.9185 mL | 2.2963 mL | |
| 50 mM | 0.0735 mL | 0.3674 mL | 0.7348 mL | 1.8370 mL | |
| 60 mM | 0.0612 mL | 0.3062 mL | 0.6123 mL | 1.5308 mL | |
| 80 mM | 0.0459 mL | 0.2296 mL | 0.4593 mL | 1.1481 mL | |
| 100 mM | 0.0367 mL | 0.1837 mL | 0.3674 mL | 0.9185 mL |
ALKBH5-IN-3 Related Classifications
HY-165422 Related Classifications
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