c-Kit-IN-13
c-Kit-IN-13 (Compound I) is a c-kit kinase inhibitor. c-Kit-IN-13 inhibits the autophosphorylation of wild-type c-kit, with an IC50 of 0.3 nM for pKIT. c-Kit-IN-13 inhibits Exon 11 KIT, with an IC50 of 0.9 nM. c-Kit-IN-13 can be used in the research of mast cell-mediated diseases such as urticaria.
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- CAS No.: 3041025-10-6
- Formule: C27H28FN9O2
- Masse moléculaire:529.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 0.3 nM (pKIT); 0.9 nM (Exon 11 KIT)[1]
Chemical Information
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CAS No. 3041025-10-6
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Masse moléculaire 529.57
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Formule C27H28FN9O2
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SMILES
CC1=NN(C=C1C2=CC3=C(C=NN3C=C2)C(NC4=C(C=C(C(C5=NN(N=N5)C6CC6)=C4)F)C)=O)CC(C)(O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
c-Kit-IN-13 Related Classifications
HY-180652 Related Classifications
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