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Cat. No.: HY-N14171

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Epicorazine A

Epicorazine A has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine A also has effect on Candida albicans with a MIC of 25 μg/mL.

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CAS No.: 62256-05-7
Formule: C₁₈H₁₆N₂O₆S₂
Masse moléculaire:420.46

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Epicorazine A Chemical Structure

CAS No.: 62256-05-7

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Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.3 μM Compound: 4	Cytotoxicity against human A549 cells after 24 hrs by SRB assay Cytotoxicity against human A549 cells after 24 hrs by SRB assay	[PMID: 24370114]
HCT-116	IC₅₀	0.33 μM Compound: 4	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24370114]
HL-60	IC₅₀	0.05 μM Compound: 4	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 24370114]
K562	IC₅₀	1.5 μM Compound: 4	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 24370114]
MGC-803	IC₅₀	2.7 μM Compound: 4	Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay	[PMID: 24370114]

Chemical Information

CAS No. 62256-05-7
Masse moléculaire 420.46
Formule C₁₈H₁₆N₂O₆S₂
SMILES

O=C1[C@@]23N(C([C@@]4(SS3)N1[C@@]5([H])[C@](C(C=C[C@@H]5O)=O)([H])C4)=O)[C@@]6([H])[C@](C(C=C[C@@H]6O)=O)([H])C2
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. G Deffieux, et al. New antibiotics from the fungus Epicoccum nigrum. II. Epicorazine A: structure elucidation and absolute configuration. J Antibiot (Tokyo). 1978 Nov;31(11):1102-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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