ASPG - asparaginase Gene
Also Known as GPA/WT; LYSOLP; C14orf76; hASNase1
Species: Homo sapiens
About ASPG
This gene has 9 transcripts (splice variants) and 207 orthologues. Biased expression in liver (RPKM 7.5), kidney (RPKM 3.8) and 8 other tissues.
Summary
Predicted to enable Acyltransferase activity, transferring groups Other than amino-acyl groups; asparaginase activity; and lysophospholipase activity. Predicted to be involved in asparagine metabolic process and phospholipid metabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
ASPG Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080464.3 | NP_001073933.2 | 60 kDa lysophospholipase isoform 1 |
| NM_001411060.1 | NP_001397989.1 | 60 kDa lysophospholipase isoform 2 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
ASPG Protein Structure
Asparaginase: Asparaginase, N-terminal (11 - 344)
Ank_2: Ankyrin repeats (3 copies) (407 - 495)
- 0
- 100
- 200
- 300
- 400
- 500
- 573 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
60 kDa lysophospholipase |
|
ASPG Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
ASPG | Q86U10 | CIMIP1 | Homo sapiens | Q9H1P6 | 32296183 | |
|
Intra
|
ASPG | Q86U10 | MYOZ3 | Homo sapiens | Q8TDC0 | 32296183 | |
|
Intra
|
ASPG | Q86U10 | VPS25 | Homo sapiens | Q9BRG1 | 32296183 | |
|
Intra
|
ASPG | Q86U10 | SHC3 | Homo sapiens | Q92529 | 32296183 | |
|
Intra
|
ASPG | Q86U10 | TEKT3 | Homo sapiens | Q9BXF9 | 32296183 | |
|
Intra
|
ASPG | Q86U10 | DMRT3 | Homo sapiens | Q9NQL9 | 32296183 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Esophagus Lymphoma |
|
|
| Testicular Leukemia |
|
|
| Adult Acute Lymphocytic Leukemia |
|
|
| Childhood Leukemia |
|
|
| Central Nervous System Leukemia |
|
|
| Mastoiditis |
|
|
| Leukemia, Acute Lymphoblastic |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Nom du produit |
Effect
|
Pureté |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS01101 | ASPG Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | ASPG | VGNC | VGNC:26218 |
| Macaca mulatta | ASPG | VGNC | VGNC:70101 |
| Canis familiaris | ASPG | VGNC | VGNC:50441 |
| Felis catus | ASPG | VGNC | VGNC:59975 |
| Rattus norvegicus | ASPG | RGD | RGD:708388 |
| Mus musculus | ASPG | MGD | MGI:2144822 |
| Others | ASPG | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service