HDAC8-IN-11
HDAC8-IN-11 is a ligand for target protein for pROTAC.
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- CAS No.: 3035977-24-0
- Formule: C16H25N3O2
- Masse moléculaire:291.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>33.3 μM
Compound: 6
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Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
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[PMID: 39089850] |
| A549 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
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[PMID: 39089850] |
| HCT-116 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| HCT-116 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
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[PMID: 39089850] |
| Jurkat | IC50 |
>33.3 μM
Compound: 6
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Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| Jurkat | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
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[PMID: 39089850] |
| THP-1 | IC50 |
>33.3 μM
Compound: 6
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Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| THP-1 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
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[PMID: 39089850] |
Chemical Information
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CAS No. 3035977-24-0
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Masse moléculaire 291.39
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Formule C16H25N3O2
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SMILES
O=C(C)NCC1=CC=C(C(NNCCCCCC)=O)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC8-IN-11 Related Classifications
HY-163921 Related Classifications
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