JMV 3008
JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 925239-09-4
- Formule: C36H39N7O3
- Masse moléculaire:617.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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GHSR1a 5.6 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | IC50 |
5.6 nM
Compound: 2, JMV 3008
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Antagonist activity at mouse GSH-R1a receptor expressed in HEK293 cells assessed as inhibition of ghrelin-induced calcium mobilization after 5 mins by FLIPR assay
Antagonist activity at mouse GSH-R1a receptor expressed in HEK293 cells assessed as inhibition of ghrelin-induced calcium mobilization after 5 mins by FLIPR assay
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[PMID: 22342626] |
| LLC-PK1 | IC50 |
5.6 nM
Compound: JMV 3008
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Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells
Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cells
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[PMID: 18193826] |
Chemical Information
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CAS No. 925239-09-4
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Masse moléculaire 617.74
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Formule C36H39N7O3
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SMILES
O=C([C@H]1NCCC1)N[C@@H](C2=NN=C(CCC3=CNC4=C3C=CC=C4)N2CC5=CC=C(OC)C=C5OC)CC6=CNC7=C6C=CC=C7
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JMV 3008 Related Classifications
HY-129287 Related Classifications
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